Resumo Introdugao e objetivo: As restingas sao peculiares por se estenderem ao longo do litoral em variadas extensoes, com fitofisionomias compostas por estrato variando entre herbáceo a arbóreo. O objetivo deste trabalho foi analisar o arranjo estrutural, a diversidade e a distribuigao da comunidade lenhosa de uma restinga ecotonal no litoral maranhense, nordeste do Brasil. M&M: Para amostragem da vegetagao foi utilizado o método de pontos-quadrantes (50 pontos), cujo critério de inclusao foi Perímetro a Altura do Solo > 10cm. Foram analisados os parámetros fitossociológicos, a estrutura da comunidade e o padrao de distribuigao fitogeográfica. Resultados: Foram amostradas 22 espécies, 18 géneros e 14 familias. As familias mais representativas foram Myrtaceae, Arecaceae, Fabaceae, Ochnaceae, Polygonaceae e Rubiaceae. As espécies de maiores Valores de Importancia (VI) foram Astrocaryum vulgare (20,36%), Attalea speciosa (19,40%), Himatanthus drasticus (14,72%), Chamaecrista ramosa (10,68%) e Eugenia biflora (10,27%). O índice de diversidade de Shannon foi 2,401 nat.ind-1 e a equitabilidade de Pielou 0,749. O padrao de distribuigao local mostrou que as espécies estao distribuidas aleatoriamente. Conclusoes: A estrutura e dinámica da restinga ecotonal entre os litorais amazónico e nordestino indica que a área tem riqueza e diversidade de espécies com valores semelhantes as restingas do nordeste, ressaltando a necessidade de protegao e valoragao das plantas das áreas de restinga.

Summary Background and aims: Restinga vegetation is an ecosystem that extends along the coast of Brazil in several extensions, with phytophysiognomies composed of strata varying from herbaceous to arboreal. The objective of this work was to analyze the structural arrangement, the diversity and distribution of the woody community of an ecotonal restinga on the coast of Maranhao, Northeast Brazi M&M: For sampling the vegetation, the method of points-quadrants (50 points) was used, whose inclusión criteria was Perimeter at Ground Height > 10cm. Phytosociological parameters, community structure and phytogeographic distribution pattern were analyzed. Results: The sampling resulted in 22 species, 18 genera and 14 families. The most representative families were Myrtaceae, Arecaceae, Fabaceae, Ochnaceae, Polygonaceae e Rubiaceae. The species with the highest Importance Values (IV) were Astrocaryum vulgare (20,36%), Attalea speciosa (19,40%), Himatanthus drasticus (14,72%), Chamaecrista ramosa (10,68%), and Eugenia biflora (10,27%). The Shannon's diversity index was 2,401 nat.ind-1 and Pielou's equality was 0,749. The pattern of local distribution showed that the species are randomly distributed. Conclusions: The structure and dynamics of the ecotonal restinga between the Amazon and Northeastern coastlines indicate that the area has richness and diversity of species with values similar to the restingas of the northeast, highlighting the need for protection and valuation of plants in restinga areas.

Abstract Serum hepcidin levels may increase in response to infection and inflammation. The present study investigated the effect of nonsurgical periodontal therapy (NSPT) on levels of serum hepcidin, inflammatory markers, and iron markers. An interventional study was conducted on 67 patients (age 30–65 years) without other diseases, except for chronic periodontitis (CP). Patients were allocated to either CP or control groups. The CP group received supragingival and subgingival scaling and root planing procedures, whereas the control group received supragingival scaling. Probing depth (PD), bleeding on probing, clinical attachment level (CAL), visible plaque index (VPI), serum hepcidin and interleukin-6 (IL-6) levels, high-sensitivity C-reactive protein (hs-CRP), hematological markers, and iron markers were measured at baseline and at 90 days after NSPT. The CP group had statistically significant lower mean values for mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) (p ≤ 0.05). The control group had statistically significant reductions in hemoglobin, hematocrit, MCV, and MCH (p ≤ 0.05). Serum hepcidin, IL-6, and erythrocyte sedimentation rate (ESR) levels were significantly decreased in both groups after NSPT. Periodontal markers were more markedly reduced in the CP group compared with the control group (p ≤ 0.05). These findings suggest that NSPT may reduce the serum levels of IL-6, hepcidin, and periodontal parameters.

Objetivo: avaliar o efeito do extrato hidroalcoólico de Euphorbia tirucalli (ETHE) sobre o desenvolvimento do tumor de Ehrlich em sua forma ascítica. Métodos: quinze camundongos Swiss foram inoculados via intraperitoneal com 10,44x107 células do tumor de Ehrlich e um dia depois foram divididos em dois grupos: Grupo ETHE (oito camundongos), tratados com a dose de 125mg/kg/dia de ETHE por cinco dias e Grupo Controle (sete camundongos), tratado apenas com 0,9% de solução salina isotônica em relação ao mesmo período. O tratamento foi realizado por gavagem. Dez dias após a inoculação, quatro animais de cada grupo foram sacrificados para a quantificação do número de células de tumor, do volume de fluido ascítico e do número de células da medula óssea. Os demais animais foram mantidos, para avaliar a sobrevivência. Resultados : o volume de líquido ascítico e do número de células tumorais foram menores no grupo ETHE quando comparado ao grupo controle, porém sem significância estatística. Por outro lado, a sobrevivência dos animais foi maior no grupo de ETHE, bem como, a quantidade de células de medula óssea. Conclusão: o tratamento com ETHE, após a inoculação do tumor, diminuiu o seu desenvolvimento e aumentou sobrevida, bem como, a celularidade da medula óssea, reduzindo assim, a mielossupressão presente nos animais portadores de tumor de Ehrlich.

Objective: to evaluate the effect of the Euphorbia tirucalli hydroalcoholic extract (ETHE) on the development of Ehrlich Tumor, in its ascitic form. Methods: we intraperitoneally inoculated 15 Swiss mice with 10.44 x 107 cells of Ehrlich Tumor and divided them in two groups one day after: ETHE Group (eight mice), treated with a dosage of 125 mg/kg/day of EHTE for five days; and Control Group (seven mice), treated only with 0.9% isotonic saline solution over the same period. The treatment was done by gavage. Ten days after inoculation, four mice from each group were sacrificed for quantification of tumor cell number, ascitic fluid volume and bone marrow cell number. The remaining animals were maintained to evaluate survival. Results: The ascitic fluid volume and the tumor cell number were decreased in the ETHE group when compared with the control group, but with no statistical significance. On the other hand, survival was higher in the ETHE group, as well as the number of bone marrow cells. Conclusion: Treatment with ETHE after inoculation of Ehrlich Tumor decreases its development and increases survival and the bone marrow cellularity, thus reducing the myelosuppression present in the Ehrlich Tumor bearing mice.